The expression of CD109 in B-cell acute lymphoblastic leukemia and its potential as a promising marker for minimal residual disease (MRD) detection
CD109 is upregulated in B-ALL and promotes leukemia cell proliferation and migration. Its consistent expression across disease stages suggests it may be a promising marker for MRD detection, highlighting its clinical significance in leukemia management.
Authors
- Baomin Qiao (ORCID: https://orcid.org/0000-0003-1509-9720)
- Fanggang Ren
- Yaofang Zhang (ORCID: https://orcid.org/0000-0001-7088-5260)
- Ying Gu (ORCID: https://orcid.org/0000-0001-7822-0570)
- Dan Liu (ORCID: https://orcid.org/0000-0001-8078-1318)
- Hongwei Wang (ORCID: https://orcid.org/0000-0003-3581-8892)
- Yi Chen (ORCID: https://orcid.org/0000-0001-6865-9512)
- Xiaojuan Wang (ORCID: https://orcid.org/0000-0002-3490-963X)
- Lixia Wang (ORCID: https://orcid.org/0000-0002-2304-7536)
- Yunxia Wang (ORCID: https://orcid.org/0000-0003-1951-942X)
- Zhifang Xu (ORCID: https://orcid.org/0000-0003-0365-0976)
- Jianmei Chang
- Kai Dong (ORCID: https://orcid.org/0000-0002-5964-4180)
- Ju Deng
- Shaotong Dong
Institutions
- Shanxi Medical University (CN)
- Fuyang City People's Hospital (CN)
- Deyang Stomatological Hospital (CN)
- Second Hospital of Shanxi Medical University (CN)
- Inner Mongolia Maternal and Child Health (CN)
Publication Details
- Journal
- Clinical and Experimental Medicine
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1007/s10238-025-01823-8
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00