Structural mechanisms of cellulose-based nanocomposites mimicking the structure of articular cartilage under uniaxial compression probed by <i>in situ</i> SAXS
A new method combining frontal ultrafiltration and ultrasound, followed by UV photocrosslinking enabled the fabrication of orthotropic CNC/PEGDA (poly(ethylene glycol) diacrylate) nanocomposites with the structure of articular cartilage. <i>In situ</i> SAXS compression/relaxation mechanical tests demonstrated this orthotropic organization as well as elastic behavior with a Young's modulus of 0.76 MPa, similar to articular cartilage.
Authors
- William Chèvremont (ORCID: https://orcid.org/0009-0009-1252-5860)
- Bruno Jean (ORCID: https://orcid.org/0000-0002-4157-7186)
- Mohamed Karrouch
- Nicolas Hengl (ORCID: https://orcid.org/0000-0002-6073-7317)
- Vianney Delplace (ORCID: https://orcid.org/0000-0002-3960-7833)
- Frédéric Pignon (ORCID: https://orcid.org/0000-0001-5852-3240)
- Laurent J. Michot (ORCID: https://orcid.org/0000-0002-0519-6992)
- Thomas Gibaud (ORCID: https://orcid.org/0000-0003-4826-8025)
- Didier Blésès (ORCID: https://orcid.org/0009-0009-3329-8257)
- Fanny Bosson
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Institut polytechnique de Grenoble (FR)
- École Normale Supérieure de Lyon (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- European Synchrotron Radiation Facility (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Sorbonne Université (FR)
- PHENIX laboratory (FR)
- Oniris (FR)
- Université Grenoble Alpes (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Nanoscale
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nr01942g
- Citations
- 1
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Agence Nationale de la Recherche
- European Synchrotron Radiation Facility
- Institut Carnot PolyNat