Pharmacokinetic strategies for achieving precise factor VIII control with susoctocog alfa in acquired hemophilia A
PK estimates from limited sampling effectively guided rpFVIII bolus and continuous infusion dosing. Continuous infusion provided steady FVIII levels and may offer a practical alternative to bolus dosing.
Authors
- Heiko Schenk (ORCID: https://orcid.org/0000-0003-2693-5712)
- Benjamin Seeliger (ORCID: https://orcid.org/0000-0001-7373-752X)
- Alfonso Iorio (ORCID: https://orcid.org/0000-0002-3331-8766)
- Andreas Tiede (ORCID: https://orcid.org/0000-0002-3600-8536)
- Christiane Dobbelstein
- Jan‐Evert Heeg
Institutions
- Medizinische Hochschule Hannover (DE)
- Impact (CA)
- McMaster University (CA)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1016/j.jtha.2025.07.033
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00