Prolonged dengue viremia with predominantly ocular manifestations in a lung transplant recipient
This was an unusual presentation of dengue involving an immune-privileged site in an immunocompromised host. The competing priorities of facilitating immune-mediated clearance of viraemia versus controlling ocular inflammation posed a significant therapeutic challenge. A greater understanding of the pathophysiology of dengue eye disease, including virus-mediated and immune-mediated factors, as well as the development of therapeutic options, is critically required.
Authors
- Ian Marr
- Leong Shuen Loo
- Nadine Ali (ORCID: https://orcid.org/0000-0002-3169-4776)
- Michael Zhang (ORCID: https://orcid.org/0000-0002-7067-0689)
- Jane M. Wells
Institutions
- Canberra Hospital (AU)
- Menzies School of Health Research (AU)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1186/s12879-025-11456-7
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00