Toward the standardization of radiopharmaceutical therapies: a technical note evaluating a clinical dosimetry workflow for single-time-point 177Lu SPECT/CT-based therapies

A single dosimetry workflow has demonstrated markedly large variability in absorbed dose accuracy. By evaluating the accuracy of absorbed dose, our study helped to propose a harmonized MIM SurePlan<sup>TM</sup> MRT workflow for single-time-point <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mmultiscripts><mml:mrow></mml:mrow> <mml:mrow></mml:mrow> <mml:mn>177</mml:mn></mml:mmultiscripts> </mml:math> Lu SPECT/CT-based therapies.

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Publication Details

Journal
EJNMMI Physics
Published
2025-08-14
DOI
https://doi.org/10.1186/s40658-025-00764-1
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
Field-Weighted Citation Impact
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article

Toward the standardization of radiopharmaceutical therapies: a technical note evaluating a clinical dosimetry workflow for single-time-point 177Lu SPECT/CT-based therapies

Wendy Siman, Taehyung Peter Kim, Vivek Mishra, Siju C George et al.
EJNMMI Physics
Radiopharmaceutical Chemistry and Applications
article

Toward the standardization of radiopharmaceutical therapies: a technical note evaluating a clinical dosimetry workflow for single-time-point 177Lu SPECT/CT-based therapies

Wendy Siman, Taehyung Peter Kim, Vivek Mishra, Siju C George, Santiago Aguirre
article en

Abstract

A single dosimetry workflow has demonstrated markedly large variability in absorbed dose accuracy. By evaluating the accuracy of absorbed dose, our study helped to propose a harmonized MIM SurePlan<sup>TM</sup> MRT workflow for single-time-point <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mmultiscripts><mml:mrow></mml:mrow> <mml:mrow></mml:mrow> <mml:mn>177</mml:mn></mml:mmultiscripts> </mml:math> Lu SPECT/CT-based therapies.

EJNMMI PhysicsVol. 12(1)
Georgia Institute of Technology (US), University of Illinois Urbana-Champaign (US), Florida International University (US), Miami Transplant Institute (US), University of Colorado Denver (US)
Openalex Percentile: Top 71%
Radiopharmaceutical Chemistry and Applications
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