Baculovirus-mediated production and purification of ferritin nanoparticles for rift valley fever vaccine development
These findings demonstrate the successful development of a platform for producing structurally stable, pure, and functional Gn-presenting ferritin nanoparticles, supporting their potential use for RVF vaccine development.
Authors
- Brian Kloss
- Paula M. Alves (ORCID: https://orcid.org/0000-0003-1445-3556)
- António Roldão (ORCID: https://orcid.org/0000-0003-0414-4899)
- Margarida Rodrigues (ORCID: https://orcid.org/0000-0002-0956-5935)
- Ashni Tambaclal
Institutions
- Instituto de Biologia Experimental e Tecnológica (PT)
- Columbia University (US)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- Journal of Biological Engineering
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1186/s13036-025-00550-8
- Citations
- 2
- Primary Topic
- Viral Infections and Vectors
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- European Commission
- Ministério da Educação
- National Institutes of Health
- University of California, San Francisco
- Fundação para a Ciência e a Tecnologia
- National Institute of Allergy and Infectious Diseases