miR-1270 suppresses glioblastoma development by transcriptional inhibition of nuclear factor IX
This study is the first to report the transcriptional inhibition of NFIX by miR-1270 in GBM cells. These findings suggest that targeting the miR-1270-NFIX axis may provide a promising therapeutic strategy for GBM.
Authors
- Tingzheng Pan
- Zhengwei Wang (ORCID: https://orcid.org/0000-0002-2671-9297)
- Jiani Lin
- Hongtian Zhang
- G.S. Tan (ORCID: https://orcid.org/0000-0001-6372-5584)
- Jiangang Liu (ORCID: https://orcid.org/0000-0001-9512-2761)
Institutions
- Guilin Medical University (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- Southern Medical University Shenzhen Hospital (CN)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1007/s11033-025-10915-3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Southern Medical University