Prognostic Divergence in Human Immunodeficiency Virus/Hepatitis B Virus Versus Hepatitis B Virus–Associated Hepatocellular Carcinoma After Resection: Intrahepatic Pre-S Deletions Mutants and T-Cell Depletion Under Viral Suppression

Virus-suppressed HIV/HBV-HCC showed a worse prognosis, with more Pre-S deletion mutants and more severe T-cell depletion observed in the liver, requiring further investigation of the mechanism.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-08-12
DOI
https://doi.org/10.1093/infdis/jiaf433
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic Divergence in Human Immunodeficiency Virus/Hepatitis B Virus Versus Hepatitis B Virus–Associated Hepatocellular Carcinoma After Resection: Intrahepatic Pre-S Deletions Mutants and T-Cell Depletion Under Viral Suppression

Xianglong Lan, Fengyu Hu, Haisheng Yu, Baojin Li et al.
The Journal of Infectious Diseases
Hepatitis B Virus Studies
article

Prognostic Divergence in Human Immunodeficiency Virus/Hepatitis B Virus Versus Hepatitis B Virus–Associated Hepatocellular Carcinoma After Resection: Intrahepatic Pre-S Deletions Mutants and T-Cell Depletion Under Viral Suppression

Xianglong Lan, Fengyu Hu, Haisheng Yu, Baojin Li, Quanyang Gao, Fan Yang
article en

Abstract

Virus-suppressed HIV/HBV-HCC showed a worse prognosis, with more Pre-S deletion mutants and more severe T-cell depletion observed in the liver, requiring further investigation of the mechanism.

The Journal of Infectious DiseasesVol. 232(5)
Key Laboratory of Guangdong Province (CN), Guangzhou Eighth People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 71%
Hepatitis B Virus Studies
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