Identification of a prognostic signature consisting of three macrophage-related genes for glioblastoma based on bulk and single-cell transcriptomes analyses
This study presents a macrophage-related gene signature to predict prognosis and therapeutic response in GBM. ISG20, PARP12 and IFIT5 are interferon-stimulated genes, and further investigations may provide new insights into the interplay between macrophages and interferon signaling in GBM.
Authors
- Chuanbiao Chen
- Hongyu Liu (ORCID: https://orcid.org/0000-0002-1571-0385)
- Lingxiong Wang (ORCID: https://orcid.org/0000-0002-8973-8911)
- Yang Bai (ORCID: https://orcid.org/0000-0002-6991-9010)
- Lina Li (ORCID: https://orcid.org/0000-0003-3481-4574)
- Liping Zhang (ORCID: https://orcid.org/0009-0007-2428-7375)
- Yaojun Peng (ORCID: https://orcid.org/0000-0003-3652-2452)
- Lingling Cui (ORCID: https://orcid.org/0000-0002-7795-3817)
- Qiyan Wu
Institutions
- Chinese PLA General Hospital (CN)
- Hainan General Hospital (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1080/07853890.2025.2546111
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00