Tris(2,2′-bipyridyl)ruthenium(II) Electrochemiluminescence of Sugar Alcohols
Sugar alcohols are low-calorie sugar substitutes commonly used in sugar-free products. In this study, we report for the first time Ru(bpy)<sub>3</sub><sup>2+</sup> electrochemiluminescence (ECL) of sugar alcohols. Ru(bpy)<sub>3</sub><sup>2+</sup> ECL of sugar alcohols, including sorbitol, mannitol, isbitol (also called isomalt, isomaltitol, and palatinitol), maltitol, lactitol, xylitol, and erythritol, was investigated. The applicability of the Ru(bpy)<sub>3</sub><sup>2+</sup> ECL system for sugar alcohol detection was demonstrated by using sorbitol as a representative analyte. The optimized system exhibited excellent analytical performance, with a wide linear detection range from 0.5 μM to 5 mM and a low detection limit of 0.026 μM (S/N = 3). In practical applications, the system demonstrated outstanding accuracy in detecting sorbitol in pharmaceutical samples, with recovery rates ranging from 97.75 to 104.00%. These findings establish the Ru(bpy)<sub>3</sub><sup>2+</sup> ECL as an effective and sensitive method for the detection of sugar alcohols.
Authors
- Tadele Eticha (ORCID: https://orcid.org/0000-0001-8526-1493)
- Zhiyong Dong (ORCID: https://orcid.org/0000-0001-7944-7734)
- Ala’a Mhmoued Abdllh Alboull (ORCID: https://orcid.org/0000-0001-9798-4461)
- Hao Jiang (ORCID: https://orcid.org/0000-0002-0911-7307)
- Guobao Xu (ORCID: https://orcid.org/0000-0001-9747-0575)
- Tasneem Omda Edrees Isaa (ORCID: https://orcid.org/0000-0002-4082-4157)
Institutions
- University of Science and Technology of China (CN)
- Chinese Academy of Sciences (CN)
- Changchun Institute of Applied Chemistry (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1021/acs.analchem.5c02987
- Citations
- 1
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 0.73
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- China Scholarship Council
- Alliance of International Science Organizations