Chorea after cardiac surgery

Chorea after cardiac surgery (formerly post-pump chorea) is a common complication in children (estimated prevalence of 0.6%-3%) but is rare in adults; when it does occur, it is often permanent and less responsive to treatment. A 47-year-old woman developed chorea in all limbs following cardiac surgery for a pseudoaneurysm of the anastomosis along with thrombectomy of the prosthetic aortic valve (after Bentall's procedure in the past). MR scan of brain showed bilateral basal ganglia abnormalities, which partially resolved over 3 months. Despite initial treatments, her condition worsened until switching to haloperidol.

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Publication Details

Journal
Practical Neurology
Published
2025-08-14
DOI
https://doi.org/10.1136/pn-2025-004716
Primary Topic
Neurological and metabolic disorders
Type
article
Field-Weighted Citation Impact
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article

Chorea after cardiac surgery

Manuela Vaněčková, Tereza Uhrová, Petr Hollý, Hana Brožová et al.
Practical Neurology
Neurological and metabolic disorders
article

Chorea after cardiac surgery

Manuela Vaněčková, Tereza Uhrová, Petr Hollý, Hana Brožová, Petr Dušek, Petra Reková
article en

Abstract

Chorea after cardiac surgery (formerly post-pump chorea) is a common complication in children (estimated prevalence of 0.6%-3%) but is rare in adults; when it does occur, it is often permanent and less responsive to treatment. A 47-year-old woman developed chorea in all limbs following cardiac surgery for a pseudoaneurysm of the anastomosis along with thrombectomy of the prosthetic aortic valve (after Bentall's procedure in the past). MR scan of brain showed bilateral basal ganglia abnormalities, which partially resolved over 3 months. Despite initial treatments, her condition worsened until switching to haloperidol.

Practical NeurologyVol. 26(2)
Charles University (CZ), General University Hospital in Prague (CZ)
Openalex Percentile: Top 72%
Neurological and metabolic disorders
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