Management and safety of same day bilateral intravitreal anti-VEGF injections in a treat-and-extend regimen

Bilateral same day intravitreal anti-VEGF injections within a TER regimen appear to be safe with no significant increase in ocular or systemic AEs compared to unilateral treatment. Coordinating bilateral IVTs using the clinical guideline presented in this study may reduce treatment visits, ease patient burden and improve compliance. Larger prospective studies are needed to confirm safety and support standardised guidelines for bilateral IVTs.

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Publication Details

Journal
BMC Ophthalmology
Published
2025-08-14
DOI
https://doi.org/10.1186/s12886-025-04293-4
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Management and safety of same day bilateral intravitreal anti-VEGF injections in a treat-and-extend regimen

Katja Hatz, Jonas Nathanael Eschle, Christina Plasencia
BMC Ophthalmology
Retinal Diseases and Treatments
article

Management and safety of same day bilateral intravitreal anti-VEGF injections in a treat-and-extend regimen

Katja Hatz, Jonas Nathanael Eschle, Christina Plasencia
article en

Abstract

Bilateral same day intravitreal anti-VEGF injections within a TER regimen appear to be safe with no significant increase in ocular or systemic AEs compared to unilateral treatment. Coordinating bilateral IVTs using the clinical guideline presented in this study may reduce treatment visits, ease patient burden and improve compliance. Larger prospective studies are needed to confirm safety and support standardised guidelines for bilateral IVTs.

BMC OphthalmologyVol. 25(1)
University of Basel (CH), Vista Klinik (CH), European Organization for Nuclear Research (CH)
Universität Basel
Openalex Percentile: Top 69%
Retinal Diseases and Treatments
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