Correlation With Dysplasia Severity and Malignant Potential of <scp>CD45RO</scp> <sup>+</sup> T Cell Density in <scp>OLP</scp> and <scp>OED</scp>
CD45RO<sup>+</sup> T cells show stage-specific distribution in oral epithelial dysplasia, suggesting prognostic relevance and offering insight into disease-related immune changes. These findings suggest diagnostic and therapeutic potential. With further validation in larger cohorts, CD45RO<sup>+</sup> monitoring may serve as a useful clinical tool for risk stratification and early intervention, particularly in high-grade OED.
Authors
- Qin Yu (ORCID: https://orcid.org/0009-0008-6569-0176)
- Ting Hu (ORCID: https://orcid.org/0000-0002-4642-3848)
- Shuo Sun
- Lifang Zhu
- Can Xiao (ORCID: https://orcid.org/0000-0002-0499-8643)
- Ziyue Yang (ORCID: https://orcid.org/0009-0008-2561-2325)
- J. Zhu (ORCID: https://orcid.org/0009-0005-9416-2354)
- Shi-Zhong Bian (ORCID: https://orcid.org/0009-0009-6515-4178)
Institutions
- Harvard University (US)
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Oral Diseases
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1111/odi.70062
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00