Dosimetry study of 3D-printed noncoplanar template-assisted CT-guided 125I seed implantation for the treatment of recurrent and metastatic tumors in the head and neck
3DPNCT-assisted RISI demonstrated accurate dose delivery and high reproducibility. This approach may enhance local control while minimizing radiation to organs at risk in complex head and neck anatomies. These results suggest that this technique has promising clinical applicability in complex head and neck cases; however, further validation through larger prospective studies is warranted to confirm long-term efficacy and safety.
Authors
- Aihong Bi
- Yongshi Jia
- Lingyun Qiu (ORCID: https://orcid.org/0009-0007-5974-1689)
- Qiang Li (ORCID: https://orcid.org/0000-0003-0096-7679)
- Limin Luo (ORCID: https://orcid.org/0000-0001-8954-1871)
- Wenming Zhan
- Huaxin Liu (ORCID: https://orcid.org/0000-0001-5567-959X)
- Jieni Ding
- Yucheng Li (ORCID: https://orcid.org/0000-0003-3473-3176)
- Kainan Shao (ORCID: https://orcid.org/0009-0001-2186-5455)
- Yinghao Zhang (ORCID: https://orcid.org/0000-0001-6084-3278)
- Hong Xiang (ORCID: https://orcid.org/0000-0001-7586-7846)
- Yinan Chen (ORCID: https://orcid.org/0009-0000-3605-8819)
- Weijun Chen (ORCID: https://orcid.org/0000-0003-1915-2357)
- Rong Wu (ORCID: https://orcid.org/0009-0008-0583-7463)
Institutions
- Zhejiang Chinese Medical University (CN)
- Yunnan Vocational College of Mechanical and Electrical Technology (CN)
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- Ningbo University Affiliated Hospital (CN)
- Hangzhou Medical College (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1371/journal.pone.0330271
- Primary Topic
- Boron Compounds in Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00