A randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy of the synbiotic medical food, SBD111, for the clinical dietary management of bone loss in menopausal women
These findings indicate SBD111 did not significantly reduce BMD loss for the full cohort. However, the trial produced evidence that SBD111 reduced bone loss in women with osteopenia and BMI ≥ 30.
Authors
- Douglas P. Kiel (ORCID: https://orcid.org/0000-0001-8474-0310)
- D. Davidson Easson
- Luis Vitetta (ORCID: https://orcid.org/0000-0002-7490-9298)
- Elizabeth Steels (ORCID: https://orcid.org/0000-0003-4743-2751)
- Harry Huntress (ORCID: https://orcid.org/0000-0002-9320-8884)
- Eric M. Schott (ORCID: https://orcid.org/0000-0001-6202-2799)
- Michael J. Zuscik (ORCID: https://orcid.org/0000-0003-0461-8708)
- Clifford J. Rosen (ORCID: https://orcid.org/0000-0003-3436-8199)
- Alicia E. Ballok
- Mark R. Charbonneau (ORCID: https://orcid.org/0000-0003-4893-8244)
- Gerardo Toledo (ORCID: https://orcid.org/0000-0002-8033-2149)
- Phillippa Ebelt
- Thomas G. Travison (ORCID: https://orcid.org/0000-0002-1030-7175)
- Ingmar Wolff (ORCID: https://orcid.org/0000-0003-4197-6643)
- Susan V. Bukata (ORCID: https://orcid.org/0000-0002-9229-5461)
- Maria J. Soto-Girón (ORCID: https://orcid.org/0000-0002-8033-8962)
- Klaus Engelke (ORCID: https://orcid.org/0000-0001-9875-4123)
- Amanda Rao
Institutions
- Clarion University (US)
- The University of Sydney (AU)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- University of California San Diego (US)
- MaineHealth (US)
- Hebrew SeniorLife (US)
- Solarea Bio (United States) (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Osteoporosis International
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1007/s00198-025-07650-7
- Citations
- 4
- Primary Topic
- Hip and Femur Fractures
- Type
- article
- Field-Weighted Citation Impact
- 8.03