PD-L1 expression in schistosomal granuloma: an immunohistochemical study in urinary bladder schistosomiasis
Schistosomal granuloma exhibits upregulated PD-L1 expression proportional to inflammation severity and pathogen viability, highlighting a critical immune checkpoint engagement in disease pathology.
Authors
- Rofyda Elhalaby (ORCID: https://orcid.org/0000-0001-6990-8154)
- Shady Anis (ORCID: https://orcid.org/0000-0001-6543-8060)
- Haidong Dong (ORCID: https://orcid.org/0000-0002-5782-2983)
- Mohamed E. Ahmed (ORCID: https://orcid.org/0000-0002-0054-2710)
- John C. Cheville (ORCID: https://orcid.org/0000-0002-8202-6268)
- Noura Kamel
- Wael Zeina
- Eugene D. Kwon
- Liza Nessim
Institutions
- Mayo Clinic (US)
- Cairo University (EG)
- Tanta University (EG)
- American International School in Egypt (EG)
- Tanta University Hospital (EG)
- Mayo Clinic in Arizona (US)
- National Water Research Center (EG)
Publication Details
- Journal
- Journal of Clinical Pathology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1136/jcp-2025-210271
- Primary Topic
- Amoebic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00