Hypogonadism and its associated factors among adult male type 2 diabetes mellitus patients at the university of gondar comprehensive specialized hospital, Northwest Ethiopia 2024: A comparative cross-sectional study

The prevalence of hypogonadism was markedly higher in individuals with type 2 diabetes mellitus compared to the control group, concomitant with a significantly lower mean testosterone level. Multivariate analyses identified fasting blood glucose, high-density lipoprotein levels, advanced age, the presence of diabetes, and obesity as independent risk factors for hypogonadism. Notably, modifiable factors such as obesity, in conjunction with key metabolic indicators, underscore potential targets for intervention to alleviate the burden of hypogonadism in diabetic patients.

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PLoS ONE
Published
2025-08-14
DOI
https://doi.org/10.1371/journal.pone.0329784
Citations
1
Primary Topic
Heart Rate Variability and Autonomic Control
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article
Field-Weighted Citation Impact
1.39
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article

Hypogonadism and its associated factors among adult male type 2 diabetes mellitus patients at the university of gondar comprehensive specialized hospital, Northwest Ethiopia 2024: A comparative cross-sectional study

Elias Chane, Tadele Derbew Kassie, Habtamu Wondifraw Baynes, Alebachew Fasil et al.
1 citations
PLoS ONE
Heart Rate Variability and Autonomic Control
1.39
article

Hypogonadism and its associated factors among adult male type 2 diabetes mellitus patients at the university of gondar comprehensive specialized hospital, Northwest Ethiopia 2024: A comparative cross-sectional study

Elias Chane, Tadele Derbew Kassie, Habtamu Wondifraw Baynes, Alebachew Fasil, Kassaw Demeke, Abebaw Worede, Amare Mekuanint, Getnet Fetene, Arega Zenaw, Yonatan Kinde
article en
1 citations

Abstract

The prevalence of hypogonadism was markedly higher in individuals with type 2 diabetes mellitus compared to the control group, concomitant with a significantly lower mean testosterone level. Multivariate analyses identified fasting blood glucose, high-density lipoprotein levels, advanced age, the presence of diabetes, and obesity as independent risk factors for hypogonadism. Notably, modifiable factors such as obesity, in conjunction with key metabolic indicators, underscore potential targets for intervention to alleviate the burden of hypogonadism in diabetic patients.

PLoS ONEVol. 20(8)
The University of Adelaide (AU), University of Gondar (ET), Debre Markos University (ET)
Openalex Percentile: Top 16%
Heart Rate Variability and Autonomic Control
1.39
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Hypogonadism and its associated factors among adult male type 2 diabetes mellitus patients at the university of gondar comprehensive specialized hospital, Northwest Ethiopia 2024: A comparative cross-sectional study — Elias Chane, Tadele Derbew Kassie, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS