Limited efficacy of cold and heat therapy as adjunctive treatments for local and functional outcomes of Bothrops atrox snakebite envenomation: A randomized clinical trial
Adjunctive HTG had no efficacy in treating local effects of B. atrox envenomation. Adjunctive CTG demonstrated benefits observed in pain reduction.
Authors
- João Ricardo Nickenig Vissoci (ORCID: https://orcid.org/0000-0001-7276-0402)
- Wuelton Marcelo Monteiro (ORCID: https://orcid.org/0000-0002-0848-1940)
- Érica da Silva Carvalho (ORCID: https://orcid.org/0000-0003-2528-2545)
- Mailma Costa de Almeida (ORCID: https://orcid.org/0000-0002-7412-0721)
- Kathleen Maclenny Pereira Carvalho (ORCID: https://orcid.org/0009-0002-0637-118X)
- Marco Aurélio Sartim (ORCID: https://orcid.org/0000-0003-4572-3109)
- André Sachett (ORCID: https://orcid.org/0000-0001-6078-4941)
- Fernando Val (ORCID: https://orcid.org/0000-0001-9995-0249)
- Jacqueline de Almeida Gonçalves Sachett (ORCID: https://orcid.org/0000-0001-5723-9977)
- Daniel Barros de Castro
- Felipe Queiroz Araújo (ORCID: https://orcid.org/0009-0007-0535-3648)
- Débora Nery Oliveira
- Yasmim da Silva Mendes
Institutions
- Fundação de Medicina Tropical (BR)
- Duke Institute for Health Innovation (US)
- Universidade do Estado do Amazonas (BR)
- Universidade Federal do Amazonas (BR)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1371/journal.pntd.0013423
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado do Amazonas
- Instituto Nacional de Ciência e Tecnologia da Criosfera
- National Institute on Aging