Dual VEGF-Targeting Strategy Via AAV2-Delivered sFLT-1 and shVEGF for Retinal Neovascularization Therapy
Dual inhibition with AAV2-sFLT-shVEGF offers a promising therapeutic approach for retinal neovascular diseases, demonstrating efficacy in reducing neovascularization and improving retinal health.
Authors
- Cuiting Chen
- Yabin Deng (ORCID: https://orcid.org/0000-0003-2414-9750)
- Mengyuan Wang
- Nuo Dong (ORCID: https://orcid.org/0000-0002-2423-3584)
- Mengdie Li (ORCID: https://orcid.org/0009-0000-0528-4741)
- Yi Liu (ORCID: https://orcid.org/0000-0002-3954-6102)
- Cheng Li (ORCID: https://orcid.org/0000-0002-0449-3709)
- Zeyu Liu (ORCID: https://orcid.org/0000-0002-9342-1247)
- Hongjun Huang (ORCID: https://orcid.org/0000-0001-5323-5389)
- Xiang Li (ORCID: https://orcid.org/0009-0007-3925-5878)
- Xiuqin Yang
- Zhifan Jiang
- Yong Zu
Institutions
- Xiamen University (CN)
- Quzhou City People's Hospital (CN)
- The 180th Hospital of PLA (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1167/iovs.66.11.37
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71