Does early non-improvement predict treatment failure in pharmacotherapy for obsessive-compulsive disorder? A diagnostic test accuracy meta-analysis with individual participant data
Patients with OCD who do not improve after 4 weeks of antidepressants will likely not respond to short-term treatment. Thus, a change in strategy should be considered after 4 weeks without treatment benefits.
Authors
- Damiaan Denys (ORCID: https://orcid.org/0000-0002-3191-3844)
- Jasper B. Zantvoord (ORCID: https://orcid.org/0000-0002-6475-902X)
- Taina Mattila
- Sem E Cohen (ORCID: https://orcid.org/0000-0002-9733-6146)
- Guido van Wingen (ORCID: https://orcid.org/0000-0003-3076-5891)
- T. de Boer
Institutions
- Netherlands Institute for Neuroscience (NL)
- Codarts Rotterdam (NL)
- Amsterdam Neuroscience (NL)
- Medicines Evaluation Board (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725101335
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00