Implementation of Doxy-PEP in a Diverse Sexual Health Program in Northern Manhattan: The Doxy-Care Study
This prospective cohort study evaluated the real-world effectiveness of doxycycline postexposure prophylaxis use in reducing bacterial sexually transmitted infections (STIs) within a diverse urban sexual health program. Propensity-matched analyses showed significant STI reductions, particularly in rectal <i>Chlamydia trachomatis</i> infections, among early adopters. Uptake was disproportionately higher in non-Hispanic White individuals and those more engaged in care. Findings emphasize the need for targeted outreach to improve care engagement and equitable access to this STI prevention strategy. (<i>Am J Public Health</i>. 2025;115(10):1584-1588. https://doi.org/10.2105/AJPH.2025.308209).
Authors
- Jason Zucker (ORCID: https://orcid.org/0000-0001-6987-6412)
- Daniela Quigee (ORCID: https://orcid.org/0000-0003-0928-1518)
- Lolita M. Burrell (ORCID: https://orcid.org/0000-0003-3472-523X)
- Natalie M. Neu (ORCID: https://orcid.org/0000-0001-5462-2938)
- Delivette Castor (ORCID: https://orcid.org/0000-0002-0988-9489)
- Jacob McLean (ORCID: https://orcid.org/0000-0002-4961-3487)
- Caroline Carnevale (ORCID: https://orcid.org/0000-0002-7701-3569)
- Kathrine Meyers (ORCID: https://orcid.org/0000-0002-8573-1958)
- Simian Huang (ORCID: https://orcid.org/0000-0001-5536-1231)
- Magdalena E. Sobieszczyk (ORCID: https://orcid.org/0000-0002-7112-3118)
- Edward A. Perez
- Joshua U. Klein
Institutions
- Columbia University (US)
Publication Details
- Journal
- American Journal of Public Health
- Published
- 2025-08-14
- DOI
- https://doi.org/10.2105/ajph.2025.308209
- Citations
- 1
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.18