Epidemiology and clinical characteristics of human rhinovirus in hospitalized children and adolescents with acute respiratory infections: a longitudinal study in Shenzhen, China (2019–2024)
HRV is a major pathogen in pediatric ARIs, with HRV mono-infections strongly associated with hospitalizations for acute wheezing illnesses and severe clinical outcomes. Unlike other respiratory viruses, HRV demonstrated relative resilience to NPIs and a notable post-pandemic shift in the age distribution of infections toward older children. These findings underscore HRV's ongoing public health significance and the necessity for continued surveillance.
Authors
- Xiaoying Fu (ORCID: https://orcid.org/0000-0003-4210-3510)
- Ke Cao (ORCID: https://orcid.org/0000-0003-3445-7482)
- Yanmin Bao
- Jiao Liu (ORCID: https://orcid.org/0000-0003-0304-241X)
- Wei Qiang Wang (ORCID: https://orcid.org/0000-0002-1430-1360)
- Wenjian Wang (ORCID: https://orcid.org/0000-0001-9459-3764)
- Xiaojuan Luo
- Jiehua Chen (ORCID: https://orcid.org/0000-0002-1276-3043)
- Yuejie Zheng (ORCID: https://orcid.org/0000-0002-1118-7611)
- Yunsheng Chen (ORCID: https://orcid.org/0000-0002-8520-9852)
- Z Y Ren
Institutions
- Shenzhen Children's Hospital (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1186/s12985-025-02901-9
- Citations
- 2
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Shenzhen Municipal Science and Technology Innovation Council