Prenatal particulate matter exposure and risk of bronchopulmonary dysplasia in very preterm infants: a retrospective cohort study
Maternal PM exposure, particularly during the second trimester, is significantly associated with BPD in VPIs, with heightened vulnerability in males and infants with lower GA and BW. These findings underscore the need for prenatal air quality interventions and targeted monitoring of high-risk subgroups. Future research should explore PM-induced mechanisms of fetal lung injury and validate these associations in multicentre cohorts.
Authors
- Yun Cao
- Libo Wang (ORCID: https://orcid.org/0000-0003-3745-9459)
- Jian‐Guo Zhou (ORCID: https://orcid.org/0000-0002-5021-3739)
- Yuan Lin (ORCID: https://orcid.org/0000-0001-8961-8971)
- Yingwen Wang (ORCID: https://orcid.org/0000-0003-2831-7926)
- Lan Zhang (ORCID: https://orcid.org/0000-0002-1983-9928)
- Jiayu Wang (ORCID: https://orcid.org/0000-0001-5957-4840)
- Jiayu Guo (ORCID: https://orcid.org/0009-0008-7015-6437)
- Renjie Chen (ORCID: https://orcid.org/0000-0002-9448-0820)
- Qing Wang (ORCID: https://orcid.org/0000-0002-6864-4094)
- Qinglin He
- Bowen Feng
- Yuanyuan Qi (ORCID: https://orcid.org/0000-0002-5872-3311)
- Wen He (ORCID: https://orcid.org/0000-0003-0440-8516)
Institutions
- Fudan University (CN)
- Children's Hospital of Fudan University (CN)
- Shanghai Maritime University (CN)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-100549
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Commission of Shanghai Municipality