Vitamin B-6 Deficiency Induces Anxiety-Like Behavior in Sprague-Dawley Rats by Disrupting Gut Homeostasis
VB-6 deficiency alters gut microbiota composition, SCFA synthesis, and neurotransmitter balance, leading to anxiety-like behavior. These findings underscore the role of the gut microbiota in mediating VB-6-dependent gut-brain interactions.
Authors
- Qi Yuan (ORCID: https://orcid.org/0000-0002-9837-8495)
- Robert F. Bertolo (ORCID: https://orcid.org/0000-0001-5069-5785)
- Shyamchand Mayengbam (ORCID: https://orcid.org/0000-0002-8996-1558)
- Ava Rasouli
- Khandkar Shaharina Hossain
- Sathya Amarasena
Institutions
- Memorial University of Newfoundland (CA)
Publication Details
- Journal
- Journal of Nutrition
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1016/j.tjnut.2025.08.012
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Natural Sciences and Engineering Research Council of Canada