Research Status of <i>Caenorhabditis elegans</i> Model in Toxicology and Its Applications in Forensic Science.

<i>Caenorhabditis elegans</i>, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background, highly conserved evolution, complete genome analysis and excellent fitting between experimental data and human results. It also shows unique advantages in the field of toxicology. This paper summarizes its advantages in toxicological research starting from the biological characteristics of <i>C. elegans</i>, introduces the toxicological research methods and progress based on the <i>C. elegans</i> model, focuses on demonstrating its applications in environmental forensic medicine and forensic toxicology, and looks forward to the application of the relevant results in the field of forensic science.

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Journal
PubMed
Published
2025-04-25
DOI
https://doi.org/10.12116/j.issn.1004-5619.2024.440406
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
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article

Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science.

Zhilong Shu, Xuehong Sun, Kui Zhang, Zhuo Li et al.
PubMed
Genetics, Aging, and Longevity in Model Organisms
article

Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science.

Zhilong Shu, Xuehong Sun, Kui Zhang, Zhuo Li, Y. Zeng
article en

Abstract

<i>Caenorhabditis elegans</i>, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background, highly conserved evolution, complete genome analysis and excellent fitting between experimental data and human results. It also shows unique advantages in the field of toxicology. This paper summarizes its advantages in toxicological research starting from the biological characteristics of <i>C. elegans</i>, introduces the toxicological research methods and progress based on the <i>C. elegans</i> model, focuses on demonstrating its applications in environmental forensic medicine and forensic toxicology, and looks forward to the application of the relevant results in the field of forensic science.

PubMedVol. 41(2)
West China Medical Center of Sichuan University (CN)
Openalex Percentile: Top 83%
Genetics, Aging, and Longevity in Model Organisms
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Research Status of <i>Caenorhabditis elegans</i> Model in Toxicology and Its Applications in Forensic Science. — Zhilong Shu, Xuehong Sun, et al. · PubMed (2025) | TGRS Research Map | TGRS