Application value of serum high mobility group protein B1 (HMGB1) and soluble triggering receptor-1 (sTREM-1) levels in the prognostic assessment of trauma

HMGB1 and sTREM-1 significantly increase in the early stage of trauma and are closely related to the severity of injury and poor prognosis. Combined dynamic monitoring can effectively predict complications and the risk of mortality, providing a crucial biomarker basis for early clinical intervention.

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Publication Details

Journal
Journal of Medical Biochemistry
Published
2025-08-08
DOI
https://doi.org/10.5937/jomb0-59276
Primary Topic
Trauma and Emergency Care Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Application value of serum high mobility group protein B1 (HMGB1) and soluble triggering receptor-1 (sTREM-1) levels in the prognostic assessment of trauma

Shaoheng Lin, Xubiao Ji, Heng Zhang, Dan Shan et al.
Journal of Medical Biochemistry
Trauma and Emergency Care Studies
article

Application value of serum high mobility group protein B1 (HMGB1) and soluble triggering receptor-1 (sTREM-1) levels in the prognostic assessment of trauma

Shaoheng Lin, Xubiao Ji, Heng Zhang, Dan Shan, Lulu Tang
article en

Abstract

HMGB1 and sTREM-1 significantly increase in the early stage of trauma and are closely related to the severity of injury and poor prognosis. Combined dynamic monitoring can effectively predict complications and the risk of mortality, providing a crucial biomarker basis for early clinical intervention.

Journal of Medical BiochemistryVol. 45(1)
Jiangsu University (CN), Xuzhou Medical College (CN), Second People’s Hospital of Huai’an (CN), Luoyang Central Hospital Affiliated to Zhengzhou University (CN), Qilu Hospital of Shandong University (CN), Pingjin Hospital (CN)
Good health and well-being
Openalex Percentile: Top 69%
Trauma and Emergency Care Studies
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