Comparative efficacy of intravenous immunoglobulin and protein A immunoadsorption in severe anti-NMDAR encephalitis
Our study demonstrates that both IVIg and PAIA are effective treatments for patients with severe anti-NMDAR encephalitis. However, PAIA demonstrates several distinct advantages, including earlier clinical improvement, faster antibody clearance, and a potential reduction in ICU stay.
Authors
- Meishan Xiong
- Ewen Tu (ORCID: https://orcid.org/0000-0003-3598-5455)
- Gaoya Zhou
- Yu Liu (ORCID: https://orcid.org/0000-0002-6709-8589)
- Cheng Yu (ORCID: https://orcid.org/0000-0002-4133-6083)
- Cong Lin (ORCID: https://orcid.org/0009-0002-1494-4427)
- Xuhui Tang
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Second People Hospital of Hunan (CN)
- Fourth Hospital of Changsha (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1602047
- Citations
- 1
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Natural Science Foundation of Hunan Province