Radiography and radiotherapy of the simulated human tissue environment with high-energy protons: A theoretical study

In this research, the diagnostic imaging and therapy of the environment of selected human tissues by the produced protons from fusion reactions have been simulated by using the Geant4 tool. As a result, the stopping power and range of protons with different energies in these tissues have been obtained. As an example, Bragg peaks caused by protons with energies of 60 to 150 MeV have been shown in breast tissue. Further, the penetration depth of protons, proton flux, and the secondary particle flux of neutrons and gamma with energies of 20 to 70 MeV (in the therapeutic energy range) have been investigated in the breast tissue. Finally, a comparison of the residual dose in breast tissue without a tumour and with a tumour at 60 MeV energy has been done. Therefore, with such simulations, calculations, and creative approaches, effective measures can be taken in the fields of proton imaging and proton therapy because proton radiography is a method that can be used to extract the maximum required information from different human tissues. Also, tumours located in different human tissues can be targeted and destroyed by using different energies of protons.

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Publication Details

Journal
Lithuanian Journal of Physics
Published
2025-08-12
DOI
https://doi.org/10.3952/physics.2025.65.2.3
Primary Topic
Radiation Therapy and Dosimetry
Type
article
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article

Radiography and radiotherapy of the simulated human tissue environment with high-energy protons: A theoretical study

N. Niknam, Safa Motlagh, M. Eshghi, Zohreh Parang
Lithuanian Journal of Physics
Radiation Therapy and Dosimetry
article

Radiography and radiotherapy of the simulated human tissue environment with high-energy protons: A theoretical study

N. Niknam, Safa Motlagh, M. Eshghi, Zohreh Parang
article en

Abstract

In this research, the diagnostic imaging and therapy of the environment of selected human tissues by the produced protons from fusion reactions have been simulated by using the Geant4 tool. As a result, the stopping power and range of protons with different energies in these tissues have been obtained. As an example, Bragg peaks caused by protons with energies of 60 to 150 MeV have been shown in breast tissue. Further, the penetration depth of protons, proton flux, and the secondary particle flux of neutrons and gamma with energies of 20 to 70 MeV (in the therapeutic energy range) have been investigated in the breast tissue. Finally, a comparison of the residual dose in breast tissue without a tumour and with a tumour at 60 MeV energy has been done. Therefore, with such simulations, calculations, and creative approaches, effective measures can be taken in the fields of proton imaging and proton therapy because proton radiography is a method that can be used to extract the maximum required information from different human tissues. Also, tumours located in different human tissues can be targeted and destroyed by using different energies of protons.

Lithuanian Journal of PhysicsVol. 65(2)
Openalex Percentile: Top 69%
Radiation Therapy and Dosimetry
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Radiography and radiotherapy of the simulated human tissue environment with high-energy protons: A theoretical study — N. Niknam, Safa Motlagh, et al. · Lithuanian Journal of Physics (2025) | TGRS Research Map | TGRS