Synergistic Anticancer Effects of Fibroblast Growth Factor Receptor Inhibitor and Cannabidiol in Colorectal Cancer
The combination of FGFR inhibitors and cannabidiol exhibited a synergistic effect in inducing cell death in colorectal cancer cells, likely through the ER stress pathway. This study supports the potential of combined FGFR inhibitor and CBD therapy as a promising strategy for enhancing anticancer effects in CRC.
Authors
- Chinock Cheong (ORCID: https://orcid.org/0000-0002-7723-0053)
- Yeonuk Ju (ORCID: https://orcid.org/0000-0001-7174-1218)
- Jeong‐An Gim (ORCID: https://orcid.org/0000-0001-7292-2520)
- Sanghee Kang (ORCID: https://orcid.org/0000-0002-6097-8831)
- Sun Il Lee (ORCID: https://orcid.org/0000-0002-5286-8042)
- Byung Wook Min (ORCID: https://orcid.org/0000-0002-3621-5113)
- Sang Cheul Oh (ORCID: https://orcid.org/0000-0002-0527-6001)
- Bu Gyeom Kim (ORCID: https://orcid.org/0000-0002-3793-7847)
- Jun Woo Bong (ORCID: https://orcid.org/0000-0002-9530-7069)
Institutions
- Korea University (KR)
- Soonchunhyang University (KR)
- Korea University Medical Center (KR)
- Soonchunhyang University Hospital Seoul (KR)
- Korea University (JP)
Publication Details
- Journal
- Nutrients
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3390/nu17162609
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korea University Guro Hospital
- Korea University Medicine
- National Research Foundation of Korea