Risk factors for coronary artery tortuosity: an original study

Aim . To study the relationship between hypertension (HTN) and coronary artery tortuosity (CAT), as well as to determine the predictors of coronary artery tortuosity (CAT). Material and methods . In this retrospective, non-randomized, uncontrolled study, 296 patients with coronary artery disease were examined, including 148 with and 148 without CAT according to coronary angiography. Results . CAT in patients correlated with the age of manifestation — 0,154 (p=0,008) and the duration of HTN — 0,148 (p=0,011). Logistic regression revealed the following factors influencing CAT: age of HTN manifestation (odds ratio (OR) 4,9, 95% confidence interval (CI): 1,4-20,3), body mass index (OR 4,3, 95% CI: 1,8-11,4), HTN duration (OR 4,4, 95% CI: 2,0-9,9), diabetes/impaired glucose tolerance (OR 4,6, 95% CI: 1,1-19,5) and a prior myocardial infarction (OR 3,1, 95% CI: 1,3-8,7). Conclusion . The duration and age of HTN manifestation correlated with CAT presence, while age, body mass index, diabetes, and myocardial infarction were risk factors for tortuosity development.