High prevalence but low clinical impact of acyclovir-resistant herpes simplex virus type 1 infections in patients with hematologic disorders
The prevalence of ACV-R HSV-1 was higher than reported data from the literature. Several novel mutations were discovered and could enrich the ACV-R HSV-1 database. Further studies are needed to investigate ACV resistance in other potentially related genes, such as UL5 and UL42.
Authors
- Ling-Ling Chen
- Hsueh Po-Ren
- Cheng‐Wen Lin (ORCID: https://orcid.org/0000-0003-0165-2652)
- Hsiu-Hsien Lin
- Mei-Chi Su
- Chih-Hao Chen
- Mao‐Wang Ho
Institutions
- China Medical University (TW)
- China Medical University Hospital (TW)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1016/j.jmii.2025.08.001
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Medical University
- National Science and Technology Council