Revisiting pediatric HGGs and PNETs according to the WHO CNS5 criteria: A clinical and genomic retrospective analysis
BT-targeted NGS facilitates the reclassification of pHGGs, revealing associations with CPS. Routine germline sequencing is warranted, and accurate molecular diagnosis enables a shift in treatment strategies tailored to specific pHGG subtypes.
Authors
- Hongseok Yun (ORCID: https://orcid.org/0000-0003-2776-5954)
- Seung Ah Choi (ORCID: https://orcid.org/0000-0003-4698-6445)
- Seung‐Ki Kim (ORCID: https://orcid.org/0000-0002-0039-0083)
- Sung‐Hye Park (ORCID: https://orcid.org/0000-0002-8681-1597)
- Ji Hoon Phi (ORCID: https://orcid.org/0000-0002-9603-5843)
- Joo Whan Kim (ORCID: https://orcid.org/0000-0003-2286-3301)
- Sungyoung Lee (ORCID: https://orcid.org/0000-0003-3458-1440)
Institutions
- New Generation University College (ET)
- Seoul National University Hospital (KR)
- Seoul National University Children's Hospital (KR)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf175
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Seoul National University