Epithelioid Hemangioendothelioma Arising From the Upper Mediastinum

Epithelioid hemangioendothelioma is classified by WHO as a malignancy that presents various clinical behaviors in a range of low and high grades. This rare cancer typically arises from the lung, liver, and other organs. A domestic literature review revealed only two cases originating from the external auditory canal and nasal cavity. A 68-year old female visited the hospital for an incidentally detected 3.5 cm mass in the left upper mediastinum between the common carotid and subclavian artery. An open biopsy under general anesthesia revealed the malignancy of epithelioid hemangioendothelioma. The patient underwent complete excision of the mass via transcervical approach and adjunctive radiation therapy thereafter. The patient has been followed up 2 years without any evidence of recurrence.