Data Resource Profile: The Heart Valve Society (HVS) Mitral and Tricuspid Valve Database

Background Prospective multicenter and standardized databases are essential to monitor and improve patients’ care. This article outlines the Heart Valve Society (HVS) Mitral and Tricuspid Valve Database that aims to track patients’ journeys with mitral and/or tricuspid valve disease through their lifetime. Methods The database focuses on the adult patients undergoing surgical or transcatheter intervention(s) for mitral and/or tricuspid valve disease. It is designed as a platform for ambispective observational cohort studies. Participating centers may contribute consecutively or based on an initiated project. The processes of ensuring high data quality are described. Results The database captures 78 outcome variables (14 clinical and 64 imaging), and 293 case-mix/baseline variables. Additionally, 2 patient-reported outcome measures are implemented in the database: the EQ-5D-5L and the Impact on Mental Health & Daily Activities questionnaire (IDCV). The outcomes and their respective definitions are harmonized with the International Consortium for Health Outcomes Measurement (ICHOM) Standard Set of Patient-Centered Outcome Measures for Heart Valve Disease (HVD). Participating centers can extract their own data for a local analysis, and proposals for multicenter studies are highly welcome. The database fully complies with the General Data Protection Regulation and the Health Insurance Portability and Accountability Act regulation, ensuring privacy through pseudonymized and anonymized data extracts. Conclusions The HVS Mitral and Tricuspid Valve Database is an interdisciplinary initiative that involves cardiologists, cardiac surgeons, and basic scientists contributing to the global standardization of data capture and governance.