Regulator of chromosome condensation 1 and broad-complex, tramtrack and bric a brac domain-containing protein is involved in ovarian cancer growth and drug resistance
RCBTB1 may regulate the NF1/Ras signaling axis, which is critical for OC and MEK inhibitor resistance. This research offers a unique therapeutic approach for ovaries with KRAS mutations and uncovers a previously unknown connection between RCBTB1 and NF1/Ras signaling.
Authors
- Bangruo Qi (ORCID: https://orcid.org/0000-0002-0224-0548)
- Gaowa Zhao
- Limeng Song (ORCID: https://orcid.org/0009-0000-2010-6177)
- Xiaochao Xiao
Institutions
- Shanghai Children's Medical Center (CN)
- Inner Mongolia People's Hospital (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2025-08-01
- DOI
- https://doi.org/10.25259/cytojournal_268_2024
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00