Multi-Omics Analysis Identifies Immune Regulatory Networks in Sepsis-Associated Liver Injury: Experimental Validation and Clinical Relevance
FCER1G, IL2RB, PTGDR, and XCL1 are novel T cell-related biomarkers of SILI, offering potential therapeutic targets. The study bridges bioinformatics predictions with experimental validation, advancing understanding of immune dysregulation in sepsis.
Authors
- Yiyu Hong (ORCID: https://orcid.org/0000-0001-6138-7083)
- Siting Gan (ORCID: https://orcid.org/0009-0007-5935-2536)
- Qiutong Chen
- Yuqi Zhang (ORCID: https://orcid.org/0000-0001-6629-4564)
- Mingliu Ma
- Hua Xie (ORCID: https://orcid.org/0000-0002-0207-4500)
- Zhaozhong Xu
Institutions
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/jir.s515615
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80