The role of cannabinoid agonists and antagonists on folliculogenesis and evolutionary events in the mouse ovary.
Cannabinoids modulate ovarian physiology and folliculogenesis, with CB2 receptors playing a particularly significant role. Antagonism at CB2 appeared to differentially affect cannabinoid-metabolizing enzymes in ovarian follicles and differentially affect their maturation. However, our preliminary novel findings in mice require human studies before clinical application.
Authors
- Touba Eslaminejad (ORCID: https://orcid.org/0000-0001-5920-1542)
- Vida Mirzaie (ORCID: https://orcid.org/0000-0001-7052-2013)
- Seyed Noureddin Nematollahi‐Mahani (ORCID: https://orcid.org/0000-0002-4733-1953)
- Fatemeh Sheikhbahaei (ORCID: https://orcid.org/0000-0001-7416-2764)
- Mina Behzadi
- Shayan Vafaei (ORCID: https://orcid.org/0000-0002-6182-6688)
- Fatemeh Nabipour (ORCID: https://orcid.org/0000-0001-5237-7916)
Institutions
- Mashhad University of Medical Sciences (IR)
- Kerman University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.85417.18468
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kerman University of Medical Sciences