Neural progenitor cell transplantation results in structural and functional recovery in a rat model of cerebral palsy.
The induction of hypoxia-ischemia (HI) in the uterus appears to be a reliable animal model for studying CP mechanisms. Additionally, our research demonstrates that the transplantation of NPCs is a promising therapeutic approach for treating CP. This advancement will enhance our comprehension and aid in the refinement of cellular therapeutic strategies.
Authors
- Koorosh Shahpasand (ORCID: https://orcid.org/0000-0003-2153-0564)
- Fatemeh Rouhollah (ORCID: https://orcid.org/0000-0001-5243-129X)
- Sahar Kiani (ORCID: https://orcid.org/0000-0001-7779-9998)
- Seyed Massood Nabavi (ORCID: https://orcid.org/0000-0002-9814-8083)
- Maryam Tavakoli Lakeh
Institutions
- Royan Institute (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
- Academic Center for Education, Culture and Research (IR)
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.85616.18508
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00