Investigation of the combined effects of cannabidiol plus naltrexone on alcohol craving in alcohol dependence: study protocol of a phase II randomised, double-blind, placebo-controlled, parallel-group trial – ICONICplus Trial

Authors

Tobias Link (ORCID: https://orcid.org/0000-0002-1032-4055)
Sabine Vollstädt‐Klein (ORCID: https://orcid.org/0000-0002-6210-672X)
Marietta Kirchner (ORCID: https://orcid.org/0000-0003-0294-2483)
Patrick Bach (ORCID: https://orcid.org/0000-0001-5962-019X)
Christina Klose
Torsten Kölsch
Bernd Lenz (ORCID: https://orcid.org/0000-0001-6086-0924)
Falk Kiefer (ORCID: https://orcid.org/0000-0001-7213-0398)
Anne Koopmann (ORCID: https://orcid.org/0000-0002-7261-9334)
Sina Zimmermann (ORCID: https://orcid.org/0000-0002-9122-5197)
Paul Thalmann
Marlen Pfisterer
Julia Weinberg
Stephen N. Oesterle
Bettina Thomas

Institutions

Heidelberg University (DE)
University Hospital Heidelberg (DE)
Zimmer Biomet (Germany) (DE)
Central Institute of Mental Health (DE)
Psychiatric Medical Center (AM)

Publication Details

Journal: BMJ Open
Published: 2025-08-01
DOI: https://doi.org/10.1136/bmjopen-2025-106348
Primary Topic: Cannabis and Cannabinoid Research
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Bundesministerium für Bildung und Forschung

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article

Investigation of the combined effects of cannabidiol plus naltrexone on alcohol craving in alcohol dependence: study protocol of a phase II randomised, double-blind, placebo-controlled, parallel-group trial – ICONICplus Trial

Tobias Link, Sabine Vollstädt‐Klein, Marietta Kirchner, Patrick Bach et al.

Aug 1, 2025

1 links

BMJ Open

Cannabis and Cannabinoid Research

article

Investigation of the combined effects of cannabidiol plus naltrexone on alcohol craving in alcohol dependence: study protocol of a phase II randomised, double-blind, placebo-controlled, parallel-group trial – ICONICplus Trial

Tobias Link, Sabine Vollstädt‐Klein, Marietta Kirchner, Patrick Bach, Christina Klose, Torsten Kölsch, Bernd Lenz, Falk Kiefer, Anne Koopmann, Sina Zimmermann, Paul Thalmann, Marlen Pfisterer, Julia Weinberg, Stephen N. Oesterle, Bettina Thomas

August 1, 2025article en

Abstract

No abstract available for this paper.

BMJ OpenVol. 15(8)

Heidelberg University (DE), University Hospital Heidelberg (DE), Zimmer Biomet (Germany) (DE), Central Institute of Mental Health (DE), Psychiatric Medical Center (AM)

Bundesministerium für Bildung und Forschung

Good health and well-being

Openalex Percentile: Top 77%

Cannabis and Cannabinoid Research

DOI Open Access PDF OpenAlex

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Investigation of the combined effects of cannabidiol plus naltrexone on alcohol craving in alcohol dependence: study protocol of a phase II randomised, double-blind, placebo-controlled, parallel-group trial – ICONICplus Trial — Tobias Link, Sabine Vollstädt‐Klein, et al. · BMJ Open (2025) | TGRS Research Map | TGRS