Estrogen and progesterone attenuate CD4-positive immune cell traffic to the penumbra region of rat's ischemic stroke brain.
The results of the present study showed that induction of tMCAO altered the expression of CD4<sup>+</sup> and gene expression of IL-1β in the ischemic penumbra. Moreover, E/P treatment could reverse these effects of stroke.
Authors
- Homayoun Naderian
- Sayyed Alireza Talaei (ORCID: https://orcid.org/0000-0001-9781-7313)
- Mohammad Ali Atlasi (ORCID: https://orcid.org/0000-0002-5058-9111)
- Nasim Alipour (ORCID: https://orcid.org/0000-0003-2082-3728)
- Abolfazl Azami Tameh
- Abutaleb Tamtaji
Institutions
- Islamic Azad University, Mashhad (IR)
- Kashan University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.84415.18275
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Kashan University of Medical Sciences