Prospective clinical trial of upright image-guided proton therapy for locally recurrent head and neck and brain malignancies
This first clinical evaluation of a novel gantry-less IGAPT system confirms its feasibility, safety, and promising efficacy for recurrent HN and brain cancer, with superior dosimetry and high local control rates. Its cost-effective design may improve global access to the IGAPT.
Authors
- Aron Popovtzer (ORCID: https://orcid.org/0000-0003-4428-9232)
- Yair Hillman
- A. Berger
- Alexander Pryanichnikov (ORCID: https://orcid.org/0000-0001-7959-1808)
- Ayman Salhab
- Marcel Fang (ORCID: https://orcid.org/0000-0001-8059-6913)
- Philip Blumenfeld (ORCID: https://orcid.org/0000-0003-4672-6862)
- Ella Wajnryt
- Marc Wygoda
- J. D. Feldman
- Shimshon Winograd
Institutions
- Karlsruhe Institute of Technology (DE)
- Hebrew University of Jerusalem (IL)
- Heidelberg University (DE)
- Hadassah Medical Center (IL)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1016/j.radonc.2025.111097
- Citations
- 2
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 3.77