Mortality and fracture risk in children with osteogenesis imperfecta: Results from the French nationwide hospital discharge database
Newborns with OI face significantly higher immediate and long-term in-hospital mortality than infants and children, and 126 times higher than that of the general population. Mortality remained stable post-2017 despite national guidelines. A quarter of patients had fractures at index stay, half of which involved the femur.
Authors
- Chloé Saint‐Dizier (ORCID: https://orcid.org/0009-0004-5274-2943)
- Julien Paccou (ORCID: https://orcid.org/0000-0001-6599-8623)
- Emmanuel Chazard (ORCID: https://orcid.org/0000-0001-7841-5925)
- Cécile Philippoteaux
- Christine Lefèvre
Institutions
- Université de Lille (FR)
- Université du littoral côte d'opale (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Lille’s Cardiology Hospital (FR)
- Direction Générale Déléguée aux Ressources (FR)
- École nationale supérieure de techniques avancées Bretagne (FR)
Publication Details
- Journal
- Bone
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1016/j.bone.2025.117607
- Citations
- 1
- Primary Topic
- Connective tissue disorders research
- Type
- article
- Field-Weighted Citation Impact
- 1.82