Comparison of Gentamicin Saline Solution and Normal Saline in Reducing Surgical Site Infections in Open Appendectomy: A Randomized Controlled Trial

SSIs contribute substantially to patient complications and healthcare expenses, particularly in lower-resource surgical settings. The reduction in SSI incidence using gentamicin-saline was not statistically significant when compared with normal saline as compared to gentamicin-saline irrigation did not significantly reduce SSIs compared to saline alone in uncomplicated open appendectomy. Focus should be placed on modifiable patient-related risk factors, particularly smoking, to reduce SSI incidence in clinical practice.