Induction of germ cell-like cells from deleted in azoospermia-like enhanced green fluorescent protein gene knock-in chicken somatic cells via transgenic expression of pluripotency and germ cell-specific transcription factors
Our findings offer new insights into the transcriptional regulation of chicken germ cells by identifying key factors that activate DAZL expression. These results indicated valuable opportunities for advancing germ cell induction from somatic cells, with potential applications of in vitro models for studying germ cell-specific gene regulatory pathways in avian species.
Authors
- Sun Keun Jung (ORCID: https://orcid.org/0000-0002-7787-2718)
- Hyeon Yang (ORCID: https://orcid.org/0000-0003-4162-4410)
- Tae Sub Park (ORCID: https://orcid.org/0000-0002-0372-5467)
- Bo Ram Lee (ORCID: https://orcid.org/0000-0002-0537-6205)
- Sung June Byun (ORCID: https://orcid.org/0000-0001-6909-1025)
Institutions
- Rural Development Administration (KR)
- National Institute of Ecology (KR)
Publication Details
- Journal
- Animal Bioscience
- Published
- 2025-08-12
- DOI
- https://doi.org/10.5713/ab.25.0233
- Primary Topic
- Animal Genetics and Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Rural Development Administration