Epstein-Barr virus and the origin of frailty and fatigue: A two-sample multivariable bidirectional Mendelian randomization study
EBV infection demonstrates causal links to frailty and fatigue, mediated through specific antibody responses. These findings emphasize EBV's role in chronic inflammatory pathways and highlight potential targets for clinical intervention.
Authors
- Jie Li (ORCID: https://orcid.org/0000-0002-7529-6040)
- Chen Tian (ORCID: https://orcid.org/0000-0003-2710-7628)
Institutions
- Fudan University (CN)
- Shanghai Public Health Clinical Center (CN)
- Ministry of Education (KR)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1016/j.exger.2025.112860
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00