Sexual Dimorphism of Plasma and Tissue Proteomes in Human Calcific Aortic Valve Stenosis Pathogenesis—Brief Report
This proof-of-concept analysis allows for the identification of potential sex-specific protein drug targets implicated in AS pathobiology.
Authors
- Francesca Bartoli‐Leonard (ORCID: https://orcid.org/0000-0001-7436-3873)
- Katelyn A. Perez (ORCID: https://orcid.org/0000-0003-3685-8212)
- Sasha A. Singh (ORCID: https://orcid.org/0000-0003-0929-3164)
- Florian Schlotter (ORCID: https://orcid.org/0000-0003-4840-1172)
- Cassandra L. Clift (ORCID: https://orcid.org/0000-0003-2441-4251)
- Hideyuki Higashi (ORCID: https://orcid.org/0000-0002-8286-8190)
- Mark C. Blaser (ORCID: https://orcid.org/0000-0002-3923-9786)
- Simon C. Robson (ORCID: https://orcid.org/0000-0001-6374-0194)
- Tan Pham (ORCID: https://orcid.org/0000-0002-0381-1365)
- Jochen D. Muehlschlegel (ORCID: https://orcid.org/0000-0002-6209-7253)
- Elena Aïkawa (ORCID: https://orcid.org/0000-0001-7835-2135)
- Masanori Aikawa (ORCID: https://orcid.org/0000-0002-9275-2079)
- Shiori Kuraoka (ORCID: https://orcid.org/0000-0001-9190-9479)
- Taku Kasai (ORCID: https://orcid.org/0000-0002-8075-6099)
- Simon C. Body (ORCID: https://orcid.org/0000-0001-6721-7050)
- Mandy E. Turner (ORCID: https://orcid.org/0000-0001-6431-5077)
Institutions
- Boston University (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Center for Vascular Biology Research (US)
- Norwegian Womens Public Health Association (NO)
- Center for Systems Biology (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1161/atvbaha.125.322560
- Citations
- 3
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.16