Clinical parameters predicted the progression to dementia in oldest old patients with mild cognitive impairment (MCI)
A combination of the MMSE, clock test, and Lawton's Index in a DPM model predicted progression from MCI to dementia best. P-tau and other blood biomarkers did not predict progression. Our results highlight the strength of clinical variables to predict the progression of MCI.
Authors
- Rosario Osta (ORCID: https://orcid.org/0000-0001-5687-6704)
- Andrea Calvo (ORCID: https://orcid.org/0000-0002-5122-7243)
- Pol Andrés‐Benito (ORCID: https://orcid.org/0000-0003-3000-0338)
- Mónica Povedano (ORCID: https://orcid.org/0000-0001-5146-6183)
- Pilar Mesa-Lampré
- Carlos Platero (ORCID: https://orcid.org/0000-0003-3712-8297)
- Antonio Lobo
- Nora Molina-Torres
- Concepción De La Cámara-Izquierdo
- Oscar Pérez-Berasategui
- María Abadía-Morales
Institutions
- Universidad de Zaragoza (ES)
- Bellvitge University Hospital (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Ente Vasco de la Energía (ES)
- Instituto de Investigación Biomédica de Lleida (ES)
- Instituto de Investigación Sanitaria Aragón (ES)
- Hospital Nuestra Señora de Alarcos (ES)
Publication Details
- Journal
- International Psychogeriatrics
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1016/j.inpsyc.2025.100129
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- European Commission
- Gobierno de Aragón
- Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
- Instituto de Salud Carlos III
- European Regional Development Fund