Aspirin or P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention for Acute Coronary Syndromes

In patients with ACS undergoing PCI, the benefits of short DAPT varied according to the subsequent monotherapy administered, with P2Y<sub>12</sub> inhibitor monotherapy significantly reducing NACE, any bleeding, and major bleeding, whereas aspirin monotherapy had neutral results. (Dual Antiplatelet Therapy De-Escalation Followed By Aspirin or P2Y12 Inhibitor Monotherapy after Percutaneous Coronary Intervention for Acute Coronary Syndrome: a Systematic Review and Meta-analysis; CRD42025645844).

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Publication Details

Journal
JACC: Cardiovascular Interventions
Published
2025-08-01
DOI
https://doi.org/10.1016/j.jcin.2025.05.044
Citations
9
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
12.49
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article

Aspirin or P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention for Acute Coronary Syndromes

Luis Ortega‐Paz, Antonio Greco, Mattia Galli, Claudio Laudani et al.
9 citations
JACC: Cardiovascular Interventions
Antiplatelet Therapy and Cardiovascular Diseases
12.49
article

Aspirin or P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention for Acute Coronary Syndromes

Luis Ortega‐Paz, Antonio Greco, Mattia Galli, Claudio Laudani, G. Occhipinti, Francesco Costa, Marco Spagnolo, Daniele Giacoppo, Davide Capodanno, Dominick J Angiolillo
article en
9 citations

Abstract

In patients with ACS undergoing PCI, the benefits of short DAPT varied according to the subsequent monotherapy administered, with P2Y<sub>12</sub> inhibitor monotherapy significantly reducing NACE, any bleeding, and major bleeding, whereas aspirin monotherapy had neutral results. (Dual Antiplatelet Therapy De-Escalation Followed By Aspirin or P2Y12 Inhibitor Monotherapy after Percutaneous Coronary Intervention for Acute Coronary Syndrome: a Systematic Review and Meta-analysis; CRD42025645844).

JACC: Cardiovascular InterventionsVol. 18(15)
Twitter (United States) (US), University of Florida (US), University of Catania (IT), Maria Cecilia Hospital (IT), Centro de Investigación Biomédica en Red (ES), Hospital Clínic de Barcelona (ES), Policlinico Universitario di Catania (IT), Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco" (IT), Florida College (US)
Good health and well-being
Openalex Percentile: Top 1%
Antiplatelet Therapy and Cardiovascular Diseases
12.49
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