Identification of characteristic genes ofanddeficiency constitutions: an integrated analysis based on bioinformatics and machine learning.

This study identified C7orf60, CFL2, CYTIP, GPR183, HIAT1, KLHL15, MAPK6, and PTGS2 in <i>Yin</i> deficiency and FUT8, TAF1D, ZNF24, MAPK6, and LEPROTL1 in <i>Yang</i> deficiency as potential biomarkers, providing insights into their pathogenesis. This theory not only guides the diagnostic approach in TCM but also extends its influence to various scientific research fields.