Paclitaxel-Coated Balloon for the Treatment of Multilayer In-Stent Restenosis
Patients with ISR of multiple stent layers had higher rates of adverse stent-related events compared with patients with single-layer ISR. Treatment with a paclitaxel-coated balloon led to greater absolute risk reduction in 1-year TLF among patients with multilayer ISR compared with an uncoated balloon. (A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis [ISR] [AGENT IDE]; NCT04647253).
Authors
- Amar Krishnaswamy (ORCID: https://orcid.org/0000-0001-6048-7955)
- Wayne Batchelor (ORCID: https://orcid.org/0000-0002-3016-1150)
- Behnam Tehrani (ORCID: https://orcid.org/0000-0002-8037-7021)
- Steven Gregg Rudick (ORCID: https://orcid.org/0000-0003-0141-7126)
- J. Aaron Grantham (ORCID: https://orcid.org/0000-0003-1539-8448)
- Jeffrey Moses
- Cindy L. Grines (ORCID: https://orcid.org/0000-0003-1653-6443)
- William Bachinsky
- John D. Altman (ORCID: https://orcid.org/0000-0001-9733-2359)
- Cinthia Bateman
- Azeem Latib (ORCID: https://orcid.org/0000-0001-9035-343X)
- Ajay Jayant Kirtane (ORCID: https://orcid.org/0000-0003-0061-1058)
- J. Dawn Abbott (ORCID: https://orcid.org/0000-0002-2560-0155)
- Mustafa Ahmed (ORCID: https://orcid.org/0000-0003-0885-8645)
- Robert W. Yeh (ORCID: https://orcid.org/0000-0002-0564-4468)
- Rafael Cavalcante (ORCID: https://orcid.org/0000-0003-0158-811X)
- Suhail Dohad
- Jennifer A. Tremmel
- William Nicholson (ORCID: https://orcid.org/0009-0008-7998-4845)
- Brian Jefferson
- Robert Stoler
- Francis Zidar
- Richard Shlofmitz
Institutions
- Northside Hospital (US)
- Cedars-Sinai Medical Center (US)
- Beth Israel Deaconess Medical Center (US)
- Cleveland Clinic (US)
- Montefiore Medical Center (US)
- NewYork–Presbyterian Hospital (US)
- Arapahoe Community College (US)
- Columbia University Irving Medical Center (US)
- Rhode Island Hospital (US)
- Emory University Hospital (US)
- UPMC Central Pa (US)
- New York Hospital Queens (US)
- Boston Scientific (United States) (US)
- University of Alabama at Birmingham (US)
- Centennial Medical Center (US)
- St. Francis Hospital (US)
- St. Luke's Hospital (US)
- Christ Hospital (US)
- St. Anthony Hospital (US)
- Stanford Medicine (US)
- Cardiovascular Research Foundation (US)
- Alaska Heart and Vascular Institute (US)
- Baylor Jack and Jane Hamilton Heart and Vascular Hospital (US)
- Christ Hospital (US)
- St. Vincent's Medical Center (US)
- Columbia University (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of the American College of Cardiology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1016/j.jacc.2025.05.062
- Citations
- 4
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- Boston Scientific Corporation